Purpose : To evaluate the efficacy of cross-disciplinary point-of-care ultrasonography （POCUS） in remote rural medicine. Subjects and Methods: Subjects were patients who underwent POCUS by a local physician because of a certain complaint or physical sign to determine whether to refer them to a secondary or tertiary medical center. We evaluated the decision to refer or not refer patients after POCUS, the validity of referrals, and outcomes based on the medical records. Results and Discussion : In a span of 1 year, about 136 patients underwent POCUS. The 164 identified symptoms were categorized as 30（ 18. 3％） musculoskeletal pain, 20（ 12. 2％） abdominal pain, and 11（ 6. 7％） fever, and the 165 locations of POCUS were 49（ 29. 7％） abdomen, 46（ 27. 9％） musculoskeletal system, and 35（ 21. 2％） heart. Based on the POCUS results, 56 patients （39. 7％） were referred, while 80 （58. 8％） were not referred and managed in the clinic. The referral was appropriate in 35 patients （87. 5％）, while the referral was unnecessary in five （6. 8％）. The outcomes of those who were not referred were as follows : 61 （82. 4％） improved, eight （10. 8％） unchanged, and five （6. 8％） worse. Conclusion : Cross-disciplinary POCUS in rural medicine helps medical practitioners make referral decisions, reduces the burden on patients of going to a remote hospital, and brings them the needed treatment promptly.