1Department of Clinical Physiology, Toho University Medical Center Sakura Hospital, 2Department of Cardiovascular Surgery, Toho University Medical Center Sakura Hospital, 3Department of Cardiovascular Center, Toho University Medical Center Sakura Hospital
It is said that pregnancy in a woman with a mechanical prosthetic heart valve increases the risk of thromboembolic complications. Therefore, more thorough anticoagulation therapies are needed. Usually, warfarin is used to prevent the development of thromboembolism after mechanical prosthetic heart replacement, but it also causes fetal abnormalities if taken in early pregnancy. On the other hand, heparin therapy has less risk of teratogenicity than warfarin, but increases the risk of thromboembolic complications in pregnancy. We herein present a case of a pregnant woman with a stuck mechanical mitral valve. Before she was pregnant, her anticoagulation therapy was switched from warfarin to heparin calcium self-injection at home. Her mechanical heart valve, however, was found to be stuck 5 months after the change in therapies.