1Department of Clinical Laboratory, Uda City Hospital, 2Department of Orthopaedic Surgery, South Nara Prefecture General Medical Center, 3Department of Orthopaedic Surgery, Uda City Hospital, 4Department of Orthopaedic Surgery, Nara Medical University
Purpose: The purpose of this study was to investigate flow changes of the deep femoral vein at different exercise patterns in a lower leg immobilized using an ankle brace. Subjects and Methods: Subjects were 87 healthy individuals (average age 41 years) without any history of diabetes, cardiovascular disease, or varix. Isometric exercise was performed using three patterns: 2 times/min, 6 times/min, and 12 times/min. For each exercise, the femoral vein flow velocity (peak velocity) and vein flow volume, and the peak velocity just after exercise and the time for peak velocity to return to resting velocity (the duration of exercise effect), were measured with ultrasonic diagnostic imaging equipment. Friedman test with post hoc Holm test was used for statistical analysis (p<0.001). Results: Peak velocity mean and volume for all three exercise patterns increased significantly compared with rest (p<0.001); however, no significant difference was found among these exercise patterns. The effect of 12 times/min exercise continued significantly longer than the other exercise patterns (p<0.001). Conclusion: The 12 times/min isometric exercise showed the highest peak velocity and flow volume and the longest duration of exercise effect. In the future, exercise periods and intervals per day should be studied to identify the optimal exercise for prevention of deep venous thrombosis.