1Department of Radiology, Tsukuba Memorial Hospital, 2Department of Pathology, Tsukuba Memorial Hospital, 3Department of Breast-Thyroid-Endocrine Surgery, Tsukuba University Hospital, 4Department of Breast-Thyroid-Endocrine Surgery, University of Tsukuba Institute of Clinical Medicine
cholesterol granuloma, breast, color Doppler, twinkling artifact
We herein report a case of breast cholesterol granuloma that presented the twinkling artifact on color Doppler sonography. The patient was a 45-year-old woman who complained of a lump in her left breast. B-mode ultrasonography showed it to be a round, well-circumscribed hypoechoic mass. Some twinkling artifacts were seen on the surface of the tumor on color Doppler ultrasonography. Mammography showed a few tiny calcifications only. Cholesterol crystals are considered to be the cause of the twinkling artifact. A cholesterol granuloma should be considered in the differential diagnosis when encountering a breast tumor presenting the twinkling artifact.