Online Journal
IF値: 1.878(2021年)→1.8(2022年)


Journal of Medical Ultrasonics

にて英文誌のFull textを閲覧することができます.


1999 - Vol.26

Vol.26 No.05

Original Article(原著)

(0729 - 0735)

ジピリダモール負荷心エコー図法による心筋虚血の診断: カラー・Mモードドプラ法による Flow Propagation Velocity 計測の意義

Diagnosis of Myocardial Ischemia by Dipyridamole Stress Echocardiography: Clinical Significance of Assessment of Flow Propagation Velocity Using the Color M-mode Doppler Method

平野 豊, 山本 忠彦, 上原 久和, 小笹 義尚, 山田 覚, 井川 寛, 石川 欽司

Yutaka HIRANO, Tadahiko YAMAMOTO, Hisakazu UEHARA, Yoshihisa OZASA, Satoru YAMADA, Hiroshi IKAWA, Kinji ISHIKAWA


First Department of Internal Medicine Kinki University School of Medicine, 377-2 Ono-higashi, Osaka-Sayama-shi, Osaka-fu 589-8511, Japan

キーワード : Coronary artery disease, Dipyridamole stress echocardiography, Doppler echocardiography, Ischemia

To investigate the clinical significance of flow propagation velocity (FPV) in color M-mode Doppler echocardiography during the dipyridamole echocardiography test, we determined wall motion abnormalities and FPV, both at the baseline and after high-dose dipyridamole infusion, in 9 control subjects (group N) and 17 patients with ischemic heart disease (group I). Dipyridamole was administered intravenously at a dose of 0.56 mg/kg over 4 minutes, followed by 4 minutes with no dose, and then at a dose of 0.28 mg/kg over 2 minutes. Two-dimensional echocardiographic images were digitized and assigned in a quad-screen format for nonbiased interpretation. FPV ratio was denned as the ratio of the value at high-dose dipyridamole infusion to that at the baseline. All patients underwent coronary angiography. Significant coronary artery disease was defined as≥75% stenosis of the large coronary arteries. Wall motion abnormalities worsened or new ones developed during dipyridamole infusion in 10 patients in group I, compared with none in group N. FPV increased significantly in group N but did not increase in group I. FPV ratio was significantly lower in group I than in group N (P