後藤 亨

Tohru GOTO

横浜市立大学医学部浦舟病院第2内科

Second Department of Internal Medicine, Yokohama City University Urafune Hospital

キーワード : Fever, Hepatocellular carcinoma, Liver dysfunction, Percutaneous ethanol injection therapy, Ultrasonography

Percutaneous ethanol injection therapy (PEIT) was performed in 13 patients with hepatocellular carcinoma a total of 36 times in 16 nodules. The PEIT procedure was recorded on video tape, and more than two doctors checked to determine whether or not the injected ethanol had leaked out of the carcinomas. Antibiotic prophylaxis was not performed. The characteristics of the carcinoma (size and depth from the surface of the liver), the age and sex of the patient, and leakage of ethanol to the surface of the liver (25.7%) were not associated with fever or liver dysfunction after PEIT. Leakage of ethanol to the bottom of the liver (34. 3%) was related to fever, however, and leakage of ethanol into the vessels of the liver (48.6%) was related to liver dysfunction after PEIT. The patients recovered from these complications without treatment, and fetal complications were avoided without the use of antibiotic prophylaxis. I conclude that the injection should be stopped and patients should be followed carefully when of ethanol leakage is recognized during PEIT.