The incidence of histopathologically defined blighted ovum has been variously reported as 49% to 90% of
all spontaneous abortions. Although most cases of blighted ovum have been shown to be karyotypically
abnormal, the details of those cases diagnosed by transvaginal ultrasonography remain obscure. Here we
attempt to analyze the incidence of chromosomal abnormalities in blighted ovum and embryonic death.
Abnormal karyotypes were obtained in 13 (68%) of 19 cases of blighted ovum, and in 16 (70%) of 23 cases
of embryonic death. The proportion of abortuses with chromosomal abnormalities of low fetal viability
potential among abnormal karyotypes was significantly higher in blighted ovum (85%) than that in embryonic death (25%) (p