To evaluate the long-term prognosis for LV wall motion changes subsequent to acute myocardial infarction
(MI), we studied 52 patients using 2-dimensional echocardiography from the onset to 1-4 years after MI. Regional wall motion was improved in 21 of 28 patients (75%) without dyskinesis during the follow-up period
and in 16 of these 21 patients (76%) within a week after the onset of ML In contrast, it was improved in only
8 of 24 patients (33%) with dyskinesis within a week after the onset. Of 25 patients who showed akinesis or
severe hypokinesis seven days after the onset of MI, it was improved further in 12 patients (48%) and
worsened in only 2 (8%). In contrast, of 13 patients who showed dyskinesis at the 7th day, only 4 patients
(31%) improved and 7 (54%) worsened. Of 35 patients who showed better wall motion than akinesis at the
7th day, only 2 patients (6%) died, compared to 5 deaths among 16 patients (31%) who showed dyskinesis or
aneurysms. Tendency to wall motion improvement was almost similar in both anterior and inferior MI except
for patients who died in early stage of the disease. The number of significant coronary lesions, development
of collateral vessels, age or sex did not affect the long-term prognosis for wall motion. In 18 of 22 patients
(82%) without wall thinning as found by 2-dimensional echocardiography, there was significant improvement.
In conclusion, both the short-term and long-term prognosis for wall motion and mortality was reflected by
serial changes and severity in regional LV wall motion within a week after the onset of MI, and dyskinesis was
a strong predictor for a poor prognosis.