An Experimental Study of Hepatic Fibrosis —Ratio of Change of The Hepatic Venous Caliber of The Liver Diseases—
The Second Department of Internal Medicine, Toho University School of Medicine
Liver disease, Ultrasound diagnosis, Hepatic venous caliber, ratio of change
Using ultrasound, we measured the hepatic venous caliber in the sitting and supine positions. These results were compared with those of procollagen III peptide (P-III-P), 7S collagen and liver function tests. The three patient groups studied were healthy controls (N=43), chronic hepatitis patients (CH, N=70), and liver cirrhosis patients (LC, N=68).
In both the right and middle hepatic veins, cirrhotics had the least amount of change in the vein diameter (and therefore the lowest "ratio of change" between the sitting and supine position) followed by CH and then the controls. For the middle hepatic vein, the value for LC was 111.2±19.8%; for CH 122.0±11.9%, pr=-0.06, pr=-0.55, pr=0.76, pr=0.67, pr=0.67, pThese results suggest that the ratio of change of the hepatic venous caliber reflects elasticity of the liver, and is a useful marker for the progression of liver disease.