Online Journal
IF値: 1.878(2021年)→1.8(2022年)


Journal of Medical Ultrasonics

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1992 - Vol.19

Vol.19 No.10

Original Article(原著)

(0663 - 0669)

超音波顕微鏡を用いた悪性心膜中皮腫の検討 −心エコー図および病理組織所見との対比−

Primary Malignant Pericardial Mesothelioma Observed by Acoustic Microscopy as Compared with Histologic Type and Echocardiogram

小牧 宏一1, 宮坂 千晶3, 山田 勉2, 阿部 好伸1, 斎藤 頴1, 小沢 友紀雄1

Koichi KOMAKI1, Chiaki MIYASAKA3, Tsutomu YAMADA2, Yoshinobu ABE1, Satoshi SAITO1, Yukio OZAWA1

1日本大学医学部第二内科, 2日本大学医学部第二病理学教室, 3オリンパス光学工業

1The Second Department of Internal Medicine, Nihon University School of Medicine, 2The Second Department of Pathology, Nihon University School of Medicine, 3Olympus Optical Co. Ltd

キーワード : Acoustic microscopy, Primary pericardial malignant mesothelioma, Tissue characterization

Primary pericardial malignant mesothelioma is a rare tumor. The echocardiographic findings of 12 cases shows that there are two different types of tumor: hypoechoic and hyperechoic tumors to data (Table 1). For evaluation of tumor echogram, two cases of malignant pericardial mesothelioma were observed using a scanning acoustic microscope (SAM: OLYMPUS UH3). Case 1 (53-year-old male): epithelial type pericardial mesothelioma. The brightness of the tumor was observed to be hypoechoic, the same finding as brightness of pericardial effusion by echocardiogram. Case 2 (45-year-old male): mixed type pericardial mesothelioma. The brightness of tumor was observed to be hyperechoic, the same as the brightness of cardiac muscle by echocardiogram. SAM with a 200 MHz acoustic lens was used for examination. Using the 3Z mode method, an extensive white zone was observed in tumor of case 1 as compared with the tumor of case 2 and each myocardium. The velocity of the surface acoustic wave (Vsaw) of tissue was measured by FFT analysis of V(z) curves. Vsaw in the tumor of case 1 was lower than that in case 2 and each myocardium. The echocardiographic brightness of pericardial malignant mesothelioma was due to the acoustic homogeneity of the tissue, therefore, white zone of 3Z mode image indicates acoustic homogeneity of a specimen. SAM and echocardiography are thus useful for determining the pathologic type of pericardial mesothelioma.