1Fourth Department of Internal Medicine University of Tokyo, School of Medicine, 2Department of Endocrinology and Metabolism, Showa General Hospital
Graves' disease, Color Doppler, Destructive thyroiditis, Ultrasonography
We report here on a new method using 7.5 MHz color Doppler of Quantum QAD 1 to make precise
differential diagnoses between Graves' disease and destructive thyroiditis. Twenty-one cases of Graves'
disease, 5 cases of chronic thyroiditis, 3 cases of destructive thyroiditis, and 12 normal controls were
examined. Total flow index (TFI) was calculated as follows; TFI= [the area of intrathyroidal blood
flow]⁄ [the area of the thyroid gland]. Active Graves' disease (group A) showed an image of "thyroid
inferno." On the contrary, patients with destructive thrroiditis showed no blood flow in the destructive
changes. TFI was the highest in group A and the lowest in euthyroid cases. These results indicates that
color Doppler ultrasonography is a simple and reliable method to make precise differential diagnosis
between these two diseases. Moreover, TFI is quite a good adjunct to estimate thyroid function.