1Division of Endocrinology and Metabolism, Showa General Hospital, 2Fourth Department of Internal Medicine, School of Medicine Tokyo University, 3First Department of Internal Medicine, School of Medicine Tokyo University
Incidence of parathyroid gland hyperplasia in 35 Dialysis patients not showing clinical signs of hyperparathyroidism were investigated by applying highly sensitive ultrasonography (7.5-10 MHz). The patients were divided into two groups. Group A consisted of dialysis patients with biochemical changes (with a high concentration of plasma phosphate and high titer of alkaline phosphatase activity). Group B consisted of those patients without any biochemical changes. Enlarged parathyroid glands were present in 9 of 19 cases (47%) in A group. On the other hand, 5 of 16 cases (30%) in group B had an enlarged parathyroid gland. The parathyroid gland was smaller in group A than in group B.