Department of Obstetrics and Gynecology, School of Medicine, Tohoku University
Ultrasound guided oocyte retrieval, Transvaginal sector probe, In vitro fertilization and embryo transfer, Transvaginal oocyte retrieval
The transvaginal sector probe (5 MHz) was applied to guide the follicle puncture needle to retrieve the oocytes for in vitro fertilization and embryo transfer. Fourteen patients were stimulated by human menopausal gonadotropin (HMG) 300 IU from day 3 to day 5, 225 IU from day 6 until the mature sign of the follicles, and human chorionic gonadotropin 10,000 IU was injected, oocytes were retrieved in 13 patients (93%): the fertilization rate (67%); the cleavage rate (97%); the embryo transfer rate (77%). The transvaginal probe was covered by the gas sterilized sac, with attached guide the needle guide. The ultrasound image of follicles by the transvaginal probe was excellent and easy to handle after short experience. This result was comparable to the one with the laparoscopic oocyte retrieval. There were no serious complications following the procedure. The anesthesia needed was minimal, and the patient could tolerate the procedure well. Therefore, the transvaginal oocyte retrieval guided by the transvaginal ultrasonography will be applicable in the outpatient settings, and this will reduce the cost and stress involved in the in vitro fertilization and embryo transfer, which will be widely used in Japan in the near future.