1The First Department of Internal Medicine, Faculty of Medicine, Kyoto University, 2The Second Department of Internal Medicine, Osaka Medical College
Ménétrier's disease, Stomach, Giant rugae, Protein losing, Ultrasonography
The ultrasonic findings obtained in a patient with Ménétrier's disease are presented. A 34-year-old man was admitted because of edema and tarry stool. Laboratory examination revealed hypochromic anemia and hypoproteinemia. X-ray examination and gastroscopy showed markedly enlarged, tortuous folds (giant rugae) on the fundus and body of the stomach. Ultrasonic examination in the fasting state showed a stomach of big size, giant rugae looking like cerebral gyri, and mucous fluid within the lumen. Gastric wall and giant rugae were pliable. These ultrasonic findings were considered to be characteristic of Ménétrier's disease. Protein losing gastropathy was recognized and a diagnosis of Ménétrier's disease was made. Gastrectomy improved the clinical symptoms. We believe that ultrasonography is useful in the study of giant rugae of the stomach.