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英文誌(2004-)

Journal of Medical Ultrasonics

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1985 - Vol.12

Vol.12 No.01

Original Article(原著)

(0062 - 0070)

門脈血流量と門脈圧の同時測定による門脈血管抵抗の測定—Bモード・パルスドップラー複合法と肝臓カテーテルの併用—

Measurement of Portal Vascular Resistance in Patients with Chronic Liver Diseases by Simultaneous Measurement of Portal Blood Flow and Portal Venous Pressure

森安 史典1, 西田 修1, 伴 信之1, 中村 武史1, 越智 次郎1, 酒井 正彦1, 内野 治人1, 塚田 英昭2, 三宅 健夫2, 宋 泰成3

Fuminori MORIYASU1, Osamu NISHIDA1, Nobuyuki BAN1, Takefumi NAKAMURA1, Jiro OCHI1, Masahiko SAKAI1, Haruto UCHINO1, Hideaki TSUKADA2, Takeo MIYAKE2, Yasunari SOH3

1京都大学医学部第一内科, 2京都大学医学部老年科, 3県立尼崎病院内科

1The First Department of Internal Medicine, Kyoto University, 2The Department of Geriatrics, Kyoto University, 3The Department of Internal Medicine, Amagasaki Prefectual Hospital

キーワード : Ultrasonic duplex system, Portal vascular resistance, Portal blood flow, Portal venous pressure

 The portal vascular resistance was measured percutaneously in 28 patients with chronic liver diseases. The portal vascular resistance (PVR) was calculated from the portal blood flow (PBF), the portal venous pressure (PVP), and the hepatic venous pressure (HVP), all of which were measured simultaneously. The PVR was calculated by the equation, PVR=(PVP-HVP)/PBF. The PBF was measured by an ultrasonic duplex system composed of a real-time B-mode scanner and a pulsed Doppler flowmeter. The PBF was calculated from the cross-sectional area measured by the B-mode and the average blood flow velocity measured by the Doppler mode. The PVP was measured by percutaneous transhepatic catheterization under ultrasonic guidance and the HVP was measured by venous catheterization. The results are as follows; The PVP was 17.6±3.9 mmHg (mean±S.D.) in patients with chronic active hepatitis (CAH, n=10) and 20.3±2.4 mmHg in cirrhosis (LC, n=18). The PBF was 973±395 ml/min in CAH and 778±272 ml/min in LC. The PVR was 0.68±0.33 mmHg・ml-1・min・kgBW in CAH and 1.25±0.73 mmHg・ml-1・min・kgBW in LC. In the PVR, there was a significant difference between CAH and LC.