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英文誌(2004-)

Journal of Medical Ultrasonics

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2002 - Vol.29

Vol.29 No.02

Original Article(原著)

(J145 - J151)

心エコー図検査による加齢の心機能に対する影響の検討

Influence of Aging on Cardiac Function Examined by Echocardiography

渡辺 さち子1, 鈴木 奈美子1, 工藤 亜津子1, 鈴木 智之1, 大内 美恵子1, 後藤 百合子1, 西條 芳文2, 村山 伸樹3

Sachiko WATANABE1, Namiko SUZUKI1, Atuko KUDO1, Tomoyuki SUZUKI1, Mieko OHUCHI1, Yuriko GOTOH1, Yoshifumi SAIJO2, Nobuki MURAYAMA3

1宮城社会保険病院検査部, 2東北大学加齢医学研究所病態計測制御研究分野, 3熊本大学大学院自然科学研究科

1Department of Laboratory, Miyagi Shakaihoken Hospital, 2Institute of Development, Aging and Cancer, Tohoku University, 3Graduate School of Science and Technology, Kumamoto University

キーワード : aging, diastolic function, Doppler echocardiography, echocardiography, systolic function

We assessed the influence of aging on cardiac function using echocardiography to measure systolic and diastolic function. The study group included 494 normal subjects aged 13 to 87 years. We detemined the ratio of E and A waves of left and right ventricular inflow (LV E/A, RV E/A), left ventricular ejection fraction (LVEF), and the ratio of the pre-ejection period and ejection time of the left ventricle (PEP/ET). Both LV E/A and RV E/A decreased significantly with age of subject. Rate of decline was greater in the LV E/A than in the RV E/A, but LVEF and PEP/ET were not significantly associated with aging. The results showed decline in the left and right ventricular diastolic function with age; however, left ventricular systolic function was not affected. The results also suggest that diastolic function is more sensitive than systolic function when the natural course of a large population is studied.