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英文誌(2004-)

Journal of Medical Ultrasonics

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2000 - Vol.27

Vol.27 No.12

Case Report(症例報告)

(1477 - 1482)

甲状腺機能の改善に伴い心筋 Integrated backscatter の心周期変動に改善を認めた甲状腺機能亢進症の1例: 甲状腺機能亢進による左室心筋障害検出の可能性について

A Case of Hyperthyroidism that Demonstrated Improvement in Cyclic Variation of Integrated Back Scatter after Normalization of Thyroid Function: Detection of Myocardial Damage Induced by Hyperthyroidism

添木 武, 福田 信夫, 篠原 尚典, 田中 英治, 板東 完治, 澤田 幸, 田村 禎通

Takeshi SOEKI, Nobuo FUKUDA, Hisanori SHINOHARA, Hideji TANAKA, Kanji BANDO, Yuki SAWADA, Yoshiyuki TAMURA

国立善通寺病院循環器科・臨床研究部

Department of Cardiology and Clinical Research, National Zentsuji Hospital, 2-1-1 Senyu-cho, Zentsuji-shi, Kagawa 765-8507, Japan

キーワード : Echocardiography, Integrated backscatter, Hyperthyroidism, Myocardial damage, Natriuretic peptide

The patient was a 55-year-old woman who was admitted because of palpitation. Laboratory data on admission showed a thyroidal hyper function, a marked increase in concentration of plasma brain natriuretic peptide (BNP), and mild cardiomegaly on chest rodiogram. We diagnosed this clinical situation as primary hyperthyroidism. Thyroid function returned to normal and the palpitation ceased 1 month after treatment with thiamazole. Plasma BNP concentration decreased but remained slightly high for 4 months and returned to the normal range 11 months after admission. M-mode echocardiogram showed normal contraction of the left ventricular wall throughout the clinical course, and mitral inflow velocity by pulsed Doppler method showed the E>A pattern on admission and an abnormal relaxation pattern 4 months after admission. Cyclic variation of integrated backscatter (IB) value in the left ventricular posterior wall was small at time of admission (3.6 dB), had increased 4 months later (7.7 dB), and was close to the normal range 11 months toper admission (8.7 dB). We conclude that the IB ultrasound method is useful in evaluating myocardial damage in hyperthyroidism.