尾本 きよか¹, 伊東 紘一¹, 程 相勇², 王　　　 恰¹, 谷口 信行¹, 秋山 いわき³, 大塚 紳⁴, 水沼 洋文⁴, 小倉 重人⁴, 金澤 暁太郎⁴

Kiyoka OMOTO¹, Kouichi ITOH¹, Xiangyong CHENG², Yi WANG¹, Nobuyuki TANIGUCHI¹, Iwaki AKIYAMA³, Shin OTSUKA⁴, Hirohumi MIZUNUMA⁴, Shigeto OGURA⁴, Kyotaro KANAZAWA⁴

¹自治医科大学臨床病理, ²三谷産業株式会社, ³湘南工科大学電気工学科, ⁴自治医科大学外科

¹Department of Clinical Pathology, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi-ken 329-0498, Japan, ²Mitani Sangyo Co. , Ltd. , 2-6 Asahidai, Tatsunokuchi-machi, Nomi-gun, Ishikawa-ken 923-1211, Japan, ³Department of Electrical Engineering, Shonan Institute of Technology, Fujisawa-shi, Kanagawa-ken 251-8511, Japan, ⁴Department of Surgery, Jichi Medical School, 3311-1 Yakushiji, Minamikawachi-machi, Kawachi-gun, Tochigi-ken 329-0498, Japan

キーワード : Breast tumors, Depth-width ratio (D⁄W), Quantitative parameter, Surface-volume ratio index (S⁄V index), Three-dimensional ultrasonic images

We applied quantitative parameters in three-dimensional ultrasonic images to distinguish benign from malignant breast tumors in 29 benign cases including 8 cysts and 21 fibroadenomas, and 32 malignant cases including 23 ductal carcinomas, 2 special types of carcinoma, 1 malignant lymphoma and 6 others. This procedure involved simultaneously acquiring video data from real-time ultrasonic images and recording the original position and orientation of the probe. Both sets of data were fed directly into a desktop computer. Fuzzy reasoning and relaxation techniques were use to automatedly extract the shape of the tumor and render it in three dimensions. We then evaluated three parameters: 2D-D⁄W, the so-called depth-width ratio measured in B mode images; 3D-D⁄W; and the S⁄V index ([surface area]³⁄36π [volume]²) calculated from the three-dimensional volume extracted with this system. All three parameters were significantly higher in the malignant group (averages: 0.81, 0.64, and 11.3, respectively) than in the benign group (averages: 0.62, 0.47, and 3.78, respectively). All three parameters were thus found to be useful in differentiating the two groups.