Advanced colon cancer, Color Doppler image, Ultrasonography
Ninety-four patients with advanced colon cancer were examined by B-mode and color Doppler ultrasonography from January 1991 to December 1995 to clarify the relationship between sonographic color Doppler characteristic and surgical or histopathologic findings. Color signals were detected in 65% (61/94) of the group. B-mode echogenecity and the color signals were significantly associated. Although no color signals were present in lesions of homogeneously low echogenecity (63%), they were present in 79% of the lesions of heterogeneously high and low echogenecity. Color-signal pattern was classified as peripheral, central, or both. Color signals tended to be peripheral in lesions of homogenous low echogenecity (100%), but tended to show the central pattern in those of heterogeneous high and low echogenecity (22%). Presence of color signals is relevant to H and P factor, and, to a moderate degree, to S factor. Comparison of histopathologic and sonographic findings showed that color signals were more abundant in poorly differentiated adenocarcinomas. The presence of color signals within the tumor may come to influence prognosis.