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英文誌(2004-)

Journal of Medical Ultrasonics

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1996 - Vol.23

Vol.23 No.01

Case Report(症例報告)

(0043 - 0050)

Apical Hypertrophic Cardiomyopathy with Left Ventricular Endomyocardial Calcification

Jong Chun Park , Joo Hyung Park , Gwang Chae Gill , Myung Ho Jeong , Jeong Gwan Cho , Jung Chaee Kang

Division of Cardiology Chonnam University Hospital

キーワード : Apical hypertrophic cardiomyopathy , Endomyocardial calcification , Echocardiography

Left ventricular (LV) endomyocardial calcification is very rarely observed in apical hypertrophic cardiomyopathy (HCM). We report 4 cases of apical hypertrophic cardiomyopathy with LV endomyocardial calcification. They were 60-year-old man, 58-year-old man, 48-year-old woman, and 53-year-old man.They had only mild and infrequent cardiac symptoms; palpitation in 3, chest pain in 2, dyspnea in 2. None had a clinical evidence of systemic thromboembolism. Surface electrocardiogram showed typical findings of apical HCM; LV hypertrophy with strain and deep inversion of T waves in the left precordial leads. Two-dimensional echocardiogram revealed markedly thickened LV apex and highly-echogenic linear densities scattered along the endocardial surface of LV apex in all 4 cases. In Case 1 and 2, fluoroscopy revealed endomyocardial calcification in the LV apex and LV angiogram showed globular shaped LV cavities. In Case 2 and 3, eosinophil counts in peripheral blood were 1,180 and 1,400/mm3 restrictively. Endomyocardial biopsy disclosed multiple vacuolar degeneration of myocytes and mild interstitial fibrosis without infiltration of inflammatory cells in Case 2. In conclusion, we report 4 cases of apical HCM with LV endomyocardial calcification. The presenting symptoms were usually mild. Typical electrocardiographic and echocardiographic features of apical HCM were very useful in making a diagnosis. Clinical significance of endomyocardial calcification in apical HCM needs to be verified.