1The Second Department of Internal Medicine, University of Tokushima, School of Medicine, 2The First Department of Pathology, University of Tokushima, School of Medicine, 3Department of Surgery, National Matsudo Hospital, 4Department of Surgery, National Cancer Center Hospital
A case of leiomyosarcoma of the liver in a 65-year-old man was reported. Laboratory examinations showed mild liver dysfunction (TTT5.6, ICG R15 15%), but tumor markers including AFP were within normal limits except for slightly elevated CEA (6.8 ng/ml). Ultrasonography (US) demonstrated a smooth and round hypoechoic lesion with irregular echogenic spots in medial segment of left hepatic lobe, which was about 3.9×3.0 cm in diameter. CT scan showed a round low density area and scintigraphy showed a cold nodule. Angiography disclosed slightly irregular tumor vessels, but not tumor stain nor hypervasculanty. Hepatoma of left hepatic lobe was suspected preoperatively. The resected tumor was measured 4.0×3.7×3.5 cm in diameter and contained necrotic areas. Histologically it was a typical leiomyosarcoma with many mitotic figures.