Eighty-one fetal blood samplings were performed in 51 pregnancies in gestational weeks 17 to 38. Fetal blood was obtained using a 22 or 23-gauge needle guided by ultrasound. The indications for fetal blood sampling included NIHF, severe IUGR, fetal anomaly, hydramnion, severe toxemia, Rh incompatibility and immunodeficiency. Maternal blood contamination was present in 3 cases and puncture failed in two cases. There were 5 cases of chromosomal anomaly, 3 of trisomy-18, 1 of trisomy-21 and 1 of partial trisomy-6p. Chronic fetal distress was diagnosed by analysing fetal umbilical venous blood gases. Fetal transfusion was carried out in a case of severe Rh isoimmunization. Severe side effects of cordocentesis, except one fetal prolonged bradycardia, were not observed.