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英文誌(2004-)

Journal of Medical Ultrasonics

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1988 - Vol.15

Vol.15 No.06

Original Article(原著)

(0475 - 0483)

バセドウ病における甲状腺の血行動態測定に関する研究

Quantitative and Non-invasive Measurement of Thyroid Blood Flow in Graves' Disease

長倉 穂積1, 川内 章裕2, 伴 良雄1, 原 秀雄1, 九島 健二1, 海原 正宏1, 福成 信博2, 神谷 憲太郎2, 伊藤 国彦3, 小池 正2, 片桐 敬1

Hozumi NAGAKURA1, Akihiro KAWAUCHI2, Yoshio BAN1, Hideo HARA1, Kenji KUSHIMA1, Masahiro KAIHARA1, Nobuhiro FUKUNARI2, Kentarou KAMIYA2, Kunihiko ITO3, Tadashi KOIKE2, Takashi KATAGIRI1

1昭和大学医学部第三内科, 2昭和大学医学部外科, 3伊藤病院

1The Third Department of Internal Medicine, Showa University School of Medicine, 2Department of Surgery, Showa University School of Medicine, 3Ito Hospital

キーワード : Graves' disease, Hemodynamics, Superior thyroid artery, Duplex scan

The blood flow of common carotid and superior thyroid artery was measured using Duplex scanning system in 16 normal volunteers and 54 hyperthyroid and 44 euthyroid patients with Graves' disease.
This instrument which is equipped with 10 MHz B mode and 4.5 MHz pulse Doppler is able to measure blood flow in those arteries non-invasively and quantitatively.
In patients with Graves' disease, the diameter, time average velocity, peak velocity and flow on both arteries were significantly higher than those in normal volunteers.
After treatment all parameters of carotid artery, except for diameter, were significantly lower, while the peak velocity of superior thyroid artery was only significantly lower than those of hyperthyroid patients.
Furthermore all parameters of superior thyroid artery were significantly correlated with the size of thyroid and its peak velocity was significantly correlated with serum free thyroxine or free triiodothyronine levels. But there was no correlation between all parameters of superior thyroid artery and thyroid 123I uptake value or TSH recepter antibody activity.
From these data, it was suggested that blood flow of common carotid artery was influenced upon thyroid function, while on superior thyroid artery it was influenced upon not only thyroid function but also the size of thyroid in patients with Graves' disease.