Eighty patients diagnosed or suspected of pancreatic cancer by ultrasonography, and four patients with pancreatic cancer who were not detected by ultrasonography, were discussed. Fifty six of sixty patients with pancreatic cancer (93.3%) were first detected. Four patients (6.7%) were missed. In non-icteric patients, twenty nine of thirty three patients (87.9%) were detected by ultrasonography. Twenty four of eighty patients (30%) were false positive cases. In ultrasonography, abnormal echoic area of the pancreas with distended pancreatic duct and total enlargement with abnormal echoic level compared with surrounding pancreatic tissue were specific finding of pancreatic cancer. For detection of early pancreatic cancer, important finding were not only distended pancreatic duct, but also tiny abnormal echoic area when neighter the distended pancreatic nor bile ducts. In a few patients with gastric or uterine cancer, the distended pancreatic and bile ducts were visualized due to lymphnodes metastases invading to the pancreas.