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英文誌(2004-)

Journal of Medical Ultrasonics

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1985 - Vol.12

Vol.12 No.05

Original Article(原著)

(0373 - 0380)

急性心筋虚血の進展と左室流入血流の変化との関係 : 超音波パルス・ドプラ法による実験的検討

Relationship between Extension of Acute Myocardial Ischemia and Mitral Flow : A Study with Pulsed Doppler Echocardiography

岡本 光師1, 梶山 梧朗1, 別府 慎太郎2, 泉 司郎2, 宮武 邦夫2, 木下 直和2, 榊原 博2, 仁村 泰治2

Mitsunori OKAMOTO1, Goro KAJIYAMA1, Shintaro BEPPU2, Shiro IZUMI2, Kunio MIYATAKE2, Naokazu KINOSHITA2, Hiroshi SAKAKIBARA2, Yasuharu NIMURA2

1広島大学医学部第一内科, 2国立循環器病センター

1The First Department of Internal Medicine, Hiroshima University, School of Medicine, 2National Cardiovasular Center

キーワード : Pulsed Doppler echocardiography, Myocardial ischemia, Myocardial infarction, Mitral flow, Relaxation

 Mitral flow patterns in acute myocardial ischemia of the canine heart were investigated by pulsed Doppler echocardiography in relation to the size of myocardial ischemia. Myocardial ischemia was accomplished and extended by ligation of the coronary arteries one by one. Effects of heart rate on the mitral flow patterns were also studied by atrial pacing. Results obtained as follows: 1. With increase of pacing rate, the flow velocity of atrial filling increased. Under constant pacing rate, myocardial ischemia caused reduction of the flow velocity of rapid filling, but it did not affect the flow velocity of atrial filling. 2. The flow velocity and acceleration rate of rapid filling decreased with extension of myocardial ischemia at pacing rate of 90 /min. The change of acceleration of rapid filling well correlated with prolongation of time constant of descending limb of left ventricular pressure. 3. These results indicated that analysis of mitral flow in acute myocardial ischemia was able to provide information about the existence and extent of extension of the ischemia.