1Department of Internal Medicine, Kobe Central Municipal Hospital, 2Central Laboratory, Kobe Central Municipal Hospital, 3Mizuma Clinic
ultrasonography, Caroli's disease
Three patients with Caroli's disease in siblings were presented. Caroli's disease was suspected by ultrasound, and then confirmed by hepato-biliary scintigrams (ggm TC-PI). With ultrasound, multiple spindle-shaped cystic lesions with folds were found in the liver of all three patients. In two, a tubular structure (the intrahepatic bile duct) communicating with every cystic lesions was recognized. In one patient, a stone within the cystic lesion was visualized. Furthermore, in two cases, medullary cysts of the kidney were shown. Hepato-biliary scientigrams demonstrated multiple dilatations of the intrahepatic bile duct at excretory phase in all. We conclude that ultrasonography can diagnose Caroli's disease by the shape of the cystic lesions and the communication between the cysts and the bile ducts. If necessary, it is confirmed by hepato-biliary scintigram.